Professor Martin Ulmschneider

King's College London

Department: Chemistry
Institution: King’s College London
Email: martin.ulmschneider@kcl.ac.uk 

Research summary

My research revolves around using Computational Chemistry to understand and quantify protein-bilayer interactions, and apply this knowledge to modulate as well as de novo design membrane proteins and membrane active peptides. Towards this goal we are developing and experimentally validated computational methods that accurately capture the processes of membrane binding, folding, partitioning, and assembly into functional proteins at atomic resolution. We are further developing these methods to advance our fundamental understanding of protein-lipid interactions and to apply this knowledge to address biomedical needs in diagnosis and therapy.

Keywords

Membranes, membrane active peptides, blood brain barrier, simulation-guided design

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